In the original film, Leatherface wore three different masks: the "Killing Mask", "Old Lady Mask" and "Pretty Woman Mask". Gunnar Hansen commented: "The reason he wore a mask, according to Tobe and Kim, was that the mask really determined his personality. Who he wanted to be that day determined what mask he put on. So when Drayton comes home with Sally, Leatherface is wearing the 'Old Lady Mask' and he's wearing an apron and carrying a wooden spoon, he wants to be domestic, helpful in the kitchen. At dinner he wears a different face, the 'Pretty Woman,' which has makeup." The "Pretty Woman" outfit consists of a female wig and a black suit, as Leatherface is "dressing up" for dinner, an old deep south tradition which stems from his southern upbringing, and the "Killing Mask" is the skin mask he wears while chasing and murdering captives. Tobe Hooper also discussed the multiple masks and dinner scene on the audio commentary for The Texas Chainsaw Massacre.
Hansen later added, "The idea of the mask is that there is no personality under the mask. That was the idea in talking with Tobe and Kim. When they created the character, they said he has to put on masks to express himself because he himself can't do it. The way we tried to create him, there is nothing under the mask, which is what makes him so frightening."
The remake offered a more concrete explanation as to why Leatherface wore masks. As a child, a severe facial deformity ate away most of his nose and made him subject to cruel ridicule from his peers. Prior to killing people, he wore animal hides, cloths and leather masks that covered up the bottom of his face. Later he began to skin some of the people he killed and wore their faces as masks. In contrast to the original film, Leatherface does not seem to have different masks for different purposes, although he does change masks occasionally. He appears briefly without his mask on in one scene of remake, his face suffers badly from Deterioration and he is missing a portion of his nose. According to the Making of Texas Chainsaw Massacre: The Beginning, How Thomas loses his nose is while at the slaughterhouse searching for Chrissy, distracted by Dean calling out for her, she attacks him and cuts Thomas badly on the nose with a knife she found.
The Wildstorm comics that took place in the remake's continuity had Leatherface taking off his mask when alone with his family, something that did not occur in any of the original films.